A New Option for Your Lips

In April of last year, although no one really noticed thanks to the pandemic that was sweeping the nation, the FDA approved a new product to expand the Restylane line of dermal fillers, Restylane Kysse. Kysse is the newest filler specifically created to add volume and smooth lines on the lips.

Dr. Barrera has long used Restylane Silk to add volume and definition to the lips. But Restylane has now added Kysse to the options out there. Here’s more about this new lip filler.

What is Restylane Kysse?

Restylane Kysse is a clear injectable gel composed of hyaluronic acid. Hyaluronic acid is a naturally occurring sugar in the human body that is responsible for hydrating and plumping the skin. It does this by binding with nearby water molecules.

Restylane Kysse is specifically meant for use on the lips. Once injected, Kysse adds fullness to the lips and it helps smooth wrinkles above the upper lip (perioral lines).

It is available for patients over the age of 21.

What’s the difference with Kysse?

Kysse is the first dermal filler to be equipped with Optimal Balance Technology, also known as XpresHAn Technology. This technology enables Kysse to integrate into the tissues in the injected areas to achieve a more natural look.

Restylane Kysse is meant as a complement to Restylane Silk, which is also formulated for the lips. Silk delivers more volume, while still looking natural. Kysse is intended to add soft, subtle volume to the lips, while also smoothing wrinkles around the mouth.


To gain FDA approval, Galderma (the maker of Restylane) had to show satisfaction rates with patients in their testing of Kysse. Those phase 3 trial patients reported these results:

  • Participants noted improvement in lip fullness using a lower amount of filler when using Kysse versus other fillers.
  • 78% of participants reported satisfaction with their lip volume and lip appearance 1 year after their injections.

What are the side effects with Kysse?

The side effects with this new Restylane filler are the same as those with all hyaluronic acid fillers: possible bruising and redness at injections sites, possible lumps or nodules, and sensitivity at the injection sites. If lumps do form, they are easily removed with an injection of an enzyme that neutralizes the hyaluronic acid and erases the lumps.

Interested in adding shape to your lips? Call Dr. Barrera at (713) 468-5200 to schedule a consultation.

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