Restylane® is a safe and natural cosmetic dermal filler that restores volume and fullness to the skin to correct facial wrinkles and folds, such as nasolabial folds.

Restylane is the only cosmetic dermal filler made of non-animal-based hyaluronic acid, a natural substance that already exists in the human body. The hyaluronic acid in Restylane is a crystal-clear gel called NASHA™ or Non-Animal Stabilized Hyaluronic Acid. NASHA is completely biocompatible with human hyaluronic acid.

Restylane maintains its shape using the body's own moisture. The hyaluronic acid in Restylane is hydrophilic or "water loving." As hyaluronic acid gradually degrades, each molecule binds to more water and over time, the same volume can be maintained with less hyaluronic acid. This ability of hyaluronic acid to bind to water is what helps provide lasting results.

Unlike other hyaluronic acid-based products, such as those made from rooster combs, only Restylane is non-animal-based. This quality virtually eliminates any risk of animal-based disease transmission or allergic reaction.

Restylane has been used in more than one million treatments in over 60 countries to correct a variety of wrinkles and to enhance the appearance of the lip border. It is currently approved in the U.S. for the treatment of facial wrinkles and folds, such as nasolabial folds, which are the lines from the nose to the corners of the mouth.

Clinical studies have shown the average Restylane treatment results can last six months or even longer. The unique NASHA technology helps maintain the cosmetic effect until the injected material is nearly gone.

Restylane is proven to deliver a longer lasting effect than traditional collagen, so treatments are typically scheduled twice a year. (Individual results may vary.)

Restylane does not require any pretesting but you should take a few precautions before being treated. You should avoid using aspirin, non-steroidal anti-inflammatory medication, St. John's Wort, or high doses of Vitamin E supplements for one week prior to treatment because they may increase bruising or bleeding at the injection site. Also, if you have previously suffered from facial cold sores, there is a risk that the needle punctures could contribute to another recurrence.

Restylane is injected directly into the skin in tiny amounts by an ultra fine needle, resulting in minimal discomfort. The procedure is simple and convenient and results are practically instantaneous. To optimize your comfort during the short procedure, your physician may decide to numb the treatment area.

Since 1996, over one million Restylane treatments have been safely administered by dermatologists and plastic surgeons in more than 60 countries. This innovative treatment is now approved in the U.S. for the treatment of facial wrinkles and folds.

Restylane has a highly favorable safety profile. It's composed of Non-Animal Stabilized Hyaluronic Acid (NASHA) a substance found naturally in the human body. Restylane is fully biocompatible. There is virtually no risk of animal-based disease transmission or allergic reaction, so no allergy testing is required before use.

Based on clinical studies, Restylane treatments produce a very low occurrence of adverse events. The most commonly reported side effects were temporary redness and swelling at the injection site. These effects typically resolve within two to three days.

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